More than 7,500 people who came into contact with Ebola victims were protected from the deadly disease by a new vaccine
A vaccine for the Ebola virus has been created which is 100 per cent effective, the World Health Organisation said today.
Results from a trial in Guinea show that VSV-EBOV protected all 7,500
people who had been in close contact with Ebola patients after just a
single dose.
Although trials are continuing, the World Health
Organisation said the results were ‘extremely promising’ while the
findings were described as ‘remarkable’ by the Wellcome Trust, which
partly funded the research.
The Guinea vaccination trial began
in affected communities on 23 March 2015 and targeted family members,
neighbours and co-workers of Ebola victims.
While the vaccine up
to now shows 100 per cent efficacy in individuals, the researchers say
more conclusive evidence is needed on its capacity to protect
populations. A new trial will now include 13 to 17-year-old and possibly
6 to 12-year-old children on the basis of new evidence of the vaccine’s
safety.
“This is an extremely promising development,” said Dr Margaret Chan, Director-General of the World Health Organization.
“The credit goes to the Guinean Government, the people living in the
communities and our partners in this project. An effective vaccine will
be another very important tool for both current and future Ebola
outbreaks.”
The trial is being run by the Guinean authorities,
WHO, Médecins sans Frontières (MSF) and the Norwegian Institute of
Public Health, with support from a broad partnership of international
and national organizations.
“This is Guinea’s gift to West
Africa and the world,” said Dr. Sakoba Keita, Guinea’s national
coordinator for the Ebola response.
“The thousands of volunteers
from Conakry and other areas of Lower Guinea, but also the many Guinean
doctors, data managers and community mobilisers have contributed to
finding a line of defence against a terrible disease.”
More than
year on from the first confirmed case recorded on 23 March 2014, at
least 11,178 people have been reported as having died from the disease
in six countries; Liberia, Guinea, Sierra Leone, Nigeria, the US and
Mali.The total number of reported cases is more than 27,275.
It
is thought the outbreak was sparked by a two year old boy playing with a
fruit bat. Experts at Public Health England (PHE) studied the genetic
mutations of the virus and traced original strain back to a small
village of Meliandou in Guinea, West Africa.
The toddler died of
unidentified causes on December 3 2013 followed a week later by his
mother, then three-year-old sister and grandmother. Mourners at the
grandmother's funeral then took the virus to other villages.
Jeremy Farrar, Director of the Wellcome Trust, said: “This is a
remarkable result which shows the power of equitable international
partnerships and flexibility,” said Jeremy Farrar, Director of the
Wellcome Trust, one of the funders of the trial. “
"This
partnership also shows that such critical work is possible in the midst
of a terrible epidemic. It should change how the world responds to such
emerging infectious disease threats.
“We, and all our partners, remain fully committed to giving the world a safe and effective vaccine. ”
The findings were published in The Lancet.
Good news, Ebola vaccine manufactured with 100% success rate
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